The practice teaching of specialty to the ability training of students of economic management field is very important. Some shortcomings exist in the practical teaching of the specialty system of undergraduate, which affect cultivation of the innovative qualified personnel. The author analyzes the existing problems, designs a scientific practical teaching system cooperating the universities with the enterprise to reform the existing system. The business processes in real enterprise has been introduced to intramural simulation training base to carry out the practice teaching of specialty cooperating the universities with the enterprises. It is mainly discussing the creative research way of the shortage of practical teaching resource for undergraduate based on the summarization of the experience gained in the innovation practice of practical teaching system of the information management and information system specialty in this paper. At the same time, the author explores the way to construct the demonstrative practice base of the information and management subject to solve the practical teaching problem of the specialty. The paper also discusses a few problems remained to be solved. On the basis of experiences and analyses, the author believes that in order to promote the construction of high-quality training system, the practical teaching system which cooperating the universities with the enterprise is the effective way to break the shackle of insufficient resources and ensure the quality of practical teaching.