The effects of melting process on Zr content and grain size in ZE41A alloy were investigated in this study. The results show that the soluble Zr increases with the increased addition content of Mg-Zr master, up to 0.87%. The ratio of Zr addition content to soluble Zr content changes within 3.86-4.8. The melt temperature has little effect on soluble Zr content. Grain size grows and both soluble Zr and total Zr decrease with the prolonged isothermal holding of the melt.