Characteration of Protein Loaded Chitosan Nanoparticles at Different pH Values

Yong Liu; Yan Sun; Yan Li Li; Shao Chun Xu; Yao Xing Xu

doi:10.4028/www.scientific.net/AMR.284-286.950

Paper Titles

Bayesian Network Learn Method for Machine Tool Thermal Stability Modeling
p.932

Synthesis and Catalytic Property of V-MCM-41 Mesoporous Molecular Sieves by Atrane Route
p.936

Characterization and Thermal Properties of the Microencapsulated PCM Slurry
p.940

Study on the Preparation of Ultramicro Molybdenum Nitride Powder and Wear Properties of Its Coating
p.945

Characteration of Protein Loaded Chitosan Nanoparticles at Different pH Values
p.950

Growth and Photoluminescence Properties of ZnO Microrods
p.954

Synthesis of Nanocrystalline Silver by Warm-Vacuum-Compaction Method
p.958

Multidisciplinary Design Optimization Method and Algorithm Based on iSIGHT
p.962

Preparation of Spheric and Hollow TiO₂ Electrophoretic Nanoparticles
p.966

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 284-286Characteration of Protein Loaded Chitosan...

Characteration of Protein Loaded Chitosan Nanoparticles at Different pH Values

Abstract:

In this paper, the properties of chitosan (CS) nanoparticles (CS NPs) and Bovine Serum Albumin (BSA) loaded chitosan nanoparticles (BSA-loaded CS NPs) prepared with sodium tripolyphosphate (TPP) at different pH values were discussed. In addition, BSA encapsulation efficiency, zeta potentials and size of CS NPs and BSA-loaded CS NPs were characterized. The results indicated that sizes of CS NPs presented “V” change along with increase of pH values, while the size of BSA-loaded CS NPs showed “U” shape change. BSA encapsulation efficiency reached the biggest value when the pH value was 5.5. Zeta potentials of CS NPs and BSA-loaded CS NPs kept going down when the pH values were increasing, and positive potential of CS-loaded BSA CS NPs became higher than that of CS NPS when the pH value was more than 5.5. BSA-loaded CS NPs prepared at pH 5.5 exhibited regular and close to spherical in shape under transmission electron microscopy (TEM) sight.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Advanced Materials Research (Volumes 284-286)

Pages:

950-953

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.284-286.950

Citation:

Cite this paper

Online since:

July 2011

Authors:

Yong Liu, Yan Sun, Yan Li Li, Shao Chun Xu, Yao Xing Xu

Keywords:

Bovine Serum Albumin (BSA), Characterization, Chitosan (CS), Nanoparticle

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] T. Fujimoto, Y. Tsuchiya, M. Terao, K. Nakamura, and M. Yamamoto: Int. J. Food Mocrobiol. Vol. 112 (2006), p.96.

Google Scholar

[2] H. Yamamoto, Y. Kuno, S. Sugimoto, H. Takeuchi and Y. Kawashima: J. Controlled Release Vol. 102(2005), p.373–381.

Google Scholar

[3] B.S. Bautista, L.M. Hernandez, M.E. Bosquez and C.L. Wilson: Crop Prot. 22(2003), p.1087

Google Scholar

[4] Y. Sun, Y. Liu, Y.Z. Li, M.Z. Lv, P.W. Li, H.L. Xu and L. Wang: Carbohyd. Polym. 84(2011), p.952

Google Scholar

[5] J. Li, Q. Liu, Y.J. Liu, S.C. Liu and S.Z. Yao: Anal. Biochem. 346(2005), p.107

Google Scholar

[6] Y.C. Wang, M.C. Lin, D.M. Wang, H.J. Hsieh: Biomaterials 24(2003), p.1047

Google Scholar

[7] Y. Liu, Y. Sun, Y.L. Li, S.C. Xu, J.W. Tang, J.T. Ding, Y.X. Xu: Carbohyd. Polym. 83(2011), p.1162

Google Scholar

[8] P.K. Dutta, Shipra Tripathi, G.K. Mehrotra and Joydeep Dutta: Food Chem. Vol. 114(2009), p.1173

Google Scholar

[9] A.W. Pan, B.B. Wu, J.M. Wu: Chin. J. Chem. Vol. 20(2009), p.79

Google Scholar

[10] T.W. Wang, Q. Xu, Y. Wu, A.J. Zeng, M.J. Li and H.X. Gao: Carbohydr. Res. Vol. 344(2009), p.908

Google Scholar

[11] A.J. Wan, Y. Sun, H.L. Li. J. Appl. Polym. Sci.Vol. 114 (2009), p.2639

Google Scholar