Manufacturing Technology and Characteristics of Nerve Conduits Made of Poly(Lactic acid) Braids

Abstract:

The nerve system has the upmost role in coordinating the actions of an animal. It is, therefore, important to repair the damaged nerve to restore its functions. In this study, we braided poly(lactic acid) ply yarn into a tubular structure using a 16-spindle braiding machine, aiming at making a nerve conduit. The results showed that the poly(lactic acid) braid obtains the maximum tensile stress when the ratio of take-up gear and braid gear is 60/50. The extensibility of the produced braid makes it a suitable conduit for nerve regeneration.

• Periodical: Advanced Materials Research (Volumes 287-290)
• Pages: 2701-2704
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.287-290.2701
• Online since: July 2011
• Authors: Ching Wen Lou, Jin Jia Hu, Yueh Sheng Chen, Chao Tsang Lu, Chih Hung He, Jia Horng Lin
• Keywords: Braiding, Nerve Conduits, Poly(lactic acid) (PLA), Twist

References

[1] R.D. Madison, C.F. Da Silva and P. Dikkes: Brain Res. Vol. 447(1988), pp.325-334.

[2] M.R. Kim, J.H. Oh, H.J. Jeong and S.H. Jeong: Int J Oral Max Surg Vol. 26, (1997), pp.151-152.

[3] A.L. Woolley, J.P. Hollowell and K.M. Rich: Otolaryngology -- Head and Neck Surgery. Vol. 103(1990), pp.509-18.

[4] J. Waite, P. Marks and D. Young: The Journal of Arthroplasty. Vol. 21(2006), pp.907-910.

[5] T.W. Chung, M.C. Yang, C.C. Tseng, S.H. Sheu, S.S. Wang, Y.Y. Huang and S.D Chen: Biomaterials. Vol. 32(2011), pp.734-743.

[6] R.E. Brown, D. Erdman, S.F. Lyons and H. Suchy: J Reconstr Microsurg Vol. 12(1996), pp.149-152.

[7] X.K. Li, S.X. Cai, B. Liu, Z.L. Xu, X.Z. Dai, K.W. Ma, S.Q. Lin, L. Yang, K.L. Sung and X.B. Fu: Colloids and Surfaces B:Biointerfaces Vol. 57(2007), pp.198-203.

DOI: 10.1016/j.colsurfb.2007.02.010

[8] C.W. Lou, C.T. Lu, S.P. Wen, C.W. Lin, C.Y. Chao and J.H. Lin: Advanced Materials Research Vol. 123-125(2010), pp.177-180.

[9] J.H. Lin, C.T. Lu, Z.H. Wu, C.K. Lin, C.W. Lin and C.W. Lou: Advanced Materials Research Vol. 123-125(2010), pp.359-362.

[10] C.W. Lou, C.T. Lu, S.Y. Huang, P.C. Lu, C.C. Huang and J.H. Lin: Advanced Materials Research Vol. 123-125(2010), pp.495-498.

[11] C.Y. Chao, C.W. Lou, H.W. Sung, Y.S. Chen and J.H. Lin: Advanced Materials Research Vol. 123-125(2010), pp.979-982.

[12] J.H. Lin, C.T. Lu, C.H. He, C.C. Huang and C.W. Lou: Journal of Composite Materials Published online before print January 6(2011).

[13] J.H. Lin, C.H. Yao, Y.S. Chen, K.C. Yen, C.Y. Chao and C.W. Lou: Advanced Materials Research Vol. 97-101(2010), pp.2253-2256.

[14] C.W. Lou, C.T. Lu, C.C. Huang, H.Y. Wang and J.H. Lin: Advanced Materials Research Vol. 55-57 (2008), pp.409-412.

[15] C.W. Lou, C.H. Yao, Y.S. Chen, T.C. Hsieh, W.H. Hsing and J.H. Lin: Text Res J, Vol. 78(12008), pp.958-265.