Hemocompatibility of TiO2 Nanoparticles Composite PTFE Coating for Medical Devices

Li Li Xue; Ping Long; Huan Wei; Ying Liang

doi:10.4028/www.scientific.net/AMR.299-300.600

Paper Titles

Study on the Activation Energy of Nanocrystallization of Amorphous Fe₇₈Si₉B₁₃ Alloy Treated by Low Frequency Pulse Magnetic Field
p.584

Fabrication and Characterization of Yttrium Lanthanum Oxide Transparent Ceramics Using Powders Prepared by Different Methods
p.588

Theoretical Calculation of β Transition Temperature of Ti-6Al-4V from Valence Electron Level
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The Promotional Effect of Lanthanum Additive on the Apparent Electrocatalysis of Ti/(Ru,Ir)O_X Electrode
p.596

Hemocompatibility of TiO₂ Nanoparticles Composite PTFE Coating for Medical Devices
p.600

Effect of Synthesis Conditions on Photocatalytic Activities of Nanoparticulate TiO₂
p.604

Influence of Processing Parameters on Atmospheric Pressure Plasma Etching of Polyvinyl Alcohol Films
p.608

Photoluminescence of (Gd_1-x,Dy_x)₂O₂SO₄ Phosphors Synthesized by Homogeneous Precipitation Method
p.612

Study of Modified Properties on Electrolytic Phosphate Coatings with Nano-Al₂O₃
p.616

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Hemocompatibility of TiO₂ Nanoparticles Composite PTFE Coating for Medical Devices

Abstract:

Hemocompatibility is a key property of biomaterials that come in contact with blood. Surface modification has shown great potential for improving the hemocompatibility of biomedical materials and devices. It has been improved that TiO₂ has excellent hemocompatibility. In this study, TiO₂ nanoparticles was added into polytetrafluorethylen (PTFE) resin in order to enhance hemocompatibility of the organic coating. The surface hydrophobicity of the coatings was characterized by contact angle measurement. Systematic evaluation of hemocompatibility, including platelet adhesion and blood clotting, proved that TiO₂ nanoparticles composite PTFE coating have better hemocompatibility. It is suggested that TiO₂ nano particles can improve hemocompatibility of organic coating due to its passive surface and chemical stability.