Selenium-Containing Curcumin Polymer for Anti-Liver Fibrosis

Yi Feng Zhu; Jing Neng; Lei Lei He; Hua Dong Tang

doi:10.4028/www.scientific.net/AMR.311-313.1061

Paper Titles

Study of Thermal Stress of Iron-Boron Alloy Casing
p.1039

Application and Study of Reactive Polyacrylate Microgel in Pigment Paint of Printed Fabric
p.1044

Research on Some Key Issues of Dynamic Simulation for Workflow Process
p.1049

Preparation and Properties of Rigid Cross-Linked PVC Foam
p.1056

Selenium-Containing Curcumin Polymer for Anti-Liver Fibrosis
p.1061

Studies on Thermal Stability and Rheological Property of PU/PVDF Blend
p.1065

Study on Properties and Preparation of Thermoplastic Polyurethane Hot-Melt Adhesive
p.1071

Adsorption Performance for Ag(І) of an Ethoxycarbonyl Thiourea Chelating Resin
p.1077

Effect of Temperature and Frequency on Dynamic Mechanical Properties of Poly(Methyl Methacrylate)
p.1081

HomeAdvanced Materials ResearchAdvanced Materials Research Vols. 311-313Selenium-Containing Curcumin Polymer for...

Selenium-Containing Curcumin Polymer for Anti-Liver Fibrosis

Abstract:

A new selenium-containing curcumin polymer was synthesized by polycondensation of curcumin with dihydride, polyethylene glycol, and selenium amino acid monomers. The polymer was stable, water soluble, and injectable with a molecular weight of 6.1x10⁴ Da. The in vivo anti-liver fibrosis efficacy of the polymer was investigated with Sprague Dawley rats. The results showed the curcumin polymer had strong anti-hepafibrosis activity.

You might also be interested in these eBooks

Advanced Materials and Processes: ADME 2011

View Preview

Info:

Periodical:

Advanced Materials Research (Volumes 311-313)

Pages:

1061-1064

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.311-313.1061

Citation:

Cite this paper

Online since:

August 2011

Authors:

Yi Feng Zhu, Jing Neng, Lei Lei He, Hua Dong Tang

Keywords:

Anti-Liver Fibrosis, Curcumin Polymer, Selenium

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] P.M. Venugopal and R.S. Adluri: Adv. Exp. Med. Biol. Vol. 595 (2007), p.105.

Google Scholar

[2] H.E. Mohamed, A.A. Latif and S.M. Thabet: Vol. 22 (1998), p.107.

Google Scholar

[3] K.R. Seung and K.H. Jung: J. Appl. Pharmacol. Vol. 13 (2005), p.232.

Google Scholar

[4] B.S. Reddy and C.V. Rao: Cancer Chemoprev. Vol.1 (2004), p.169.

Google Scholar

[5] H.Tsukamoto: Alcohol. Vol. 10 (1993), p.465.

Google Scholar

[6] S.L. Friedman: J. Biol. Chem. Vol. 275 (2000), p.2247.

Google Scholar

[7] Y.J. Wang, M.H. Pan, A.L. Cheng, L.I. Lin, Y.S. Ho, C.Y. Hsieh and J.K. Lin: J. Pharm. Biomed. Anal. Vol. 15 (1997), p.1867.

Google Scholar

[8] R.A. Sharma, S.A Euden, S.L. Platton, D.N. Cooke, A. Shafayat, H.R. Hewitt, T.H. Marczylo, B. Morgan, D. Hemingway, S.M Plummer, M. Pirmohamed. A.J. Gescher and W.P. Steward: Clin. Cancer Res. 10 (2004), p.6847.

DOI: 10.1158/1078-0432.ccr-04-0744

Google Scholar

[9] J. Czuczejko, B.A. Zachara, E. Staubach-Topczewska and W. Halota: Acta Biochim. Pol. Vol. 50 (2003), p.1147.

DOI: 10.18388/abp.2003_3638

Google Scholar

[10] Y.T. He, D.W. Liu, L.Y. Ding, Q. Li and Y.H. Xiao: World J. Gastroenterol. Vol. 10 (2004), p.103.

Google Scholar