Selenium-Containing Curcumin Polymer for Anti-Liver Fibrosis
A new selenium-containing curcumin polymer was synthesized by polycondensation of curcumin with dihydride, polyethylene glycol, and selenium amino acid monomers. The polymer was stable, water soluble, and injectable with a molecular weight of 6.1x104 Da. The in vivo anti-liver fibrosis efficacy of the polymer was investigated with Sprague Dawley rats. The results showed the curcumin polymer had strong anti-hepafibrosis activity.
Y. F. Zhu et al., "Selenium-Containing Curcumin Polymer for Anti-Liver Fibrosis", Advanced Materials Research, Vols. 311-313, pp. 1061-1064, 2011