The Use of Rapid Prototyping to Fabricate Liver Tissue Engineering Scaffold
In this papers, the authors described a rapid prototyping method to produce vascularized tissue such liver scaffold for tissue engineering applications. A scaffold with interconnected channel was designed using CAD environment. The data were transferred to a Polyjet 3D Printing machine (Eden 250, Object, Israel) to generate the models. Based on the 3D Printing model, a PDMS (polydimethyl-silicone) mould was created which can be used to cast the biodegradable poly (L-lactic-co-glycolic acid) (PLGA )material. The advantages and limitations of Rapid Prototyping (RP) techniques as well as the future direction of RP development in tissue engineering scaffold fabrication were reviewed.
Liangchi Zhang, Chunliang Zhang and Zichen Chen
S. Sekou et al., "The Use of Rapid Prototyping to Fabricate Liver Tissue Engineering Scaffold", Advanced Materials Research, Vols. 328-330, pp. 658-661, 2011