Formulation of Vanillin Cross-Linked Chitosan Nanoparticles and its Characterization

Abstract:

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Chitosan nanoparticles were successfully prepared by chemical cross-linking with vanillin. The nanoparticles were spherical in shape with smooth surface, and the average particle size of chitosan nanoparticles was 141 nm. The formulation of chitosan nanoparticles is based on Shiff reaction between aldehyde group of vanillin and amino group of chitosan. Chitosan nanoparticles prepared by crosslinking with vanillin are promising vehicle for the drug delivery of various anticancer drugs in the chemotherapy of cancers.

Info:

Periodical:

Advanced Materials Research (Volumes 335-336)

Edited by:

Yun-Hae Kim, Prasad Yarlagadda, Xiaodong Zhang and Zhijiu Ai

Pages:

474-477

DOI:

10.4028/www.scientific.net/AMR.335-336.474

Citation:

G. Wang et al., "Formulation of Vanillin Cross-Linked Chitosan Nanoparticles and its Characterization", Advanced Materials Research, Vols. 335-336, pp. 474-477, 2011

Online since:

September 2011

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Price:

$35.00

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