The dynamic time-history response analysis method was employed to analyze the dynamic response of composition foundation with CFG piles. The deformation and stress distribution of composite foundation of CFG piles with different length and amount of piles under seismic wave was investigated. The results reveal that the bearing and asti-deformation capacity could be improved effectively for composite foundation under earthquake loads by increasing the length and number of pile. The vertical stress of foundation soil decreases gradually with the increase of the length and number of pile. The practice shows that CFG piles provide a positive contribution to the aseismic effect of foundation soils mass. The present research can provide some references to similar projects.