Bovine Serum Albumin Modified Mg-Al Layered Double Oxides Nanohybrids: Preparation and Potential Application as Drug Carrier

Abstract:

Biocompatible MgAl-CO3-LDH-derived layered double oxide (LDO) as the host and bovine serum albumin (BSA) as a model protein have been chosen to fabricate a novel bioinorganic nanohybrid (BSA-LDO). The structure, morphology and physicochemical properties of the obtained nanohybrids are investigated by XRD, FT-IR, SEM and UV-vis methods and the interaction between LDO and BSA molecules has been discussed. The application of these nanohybrids as drug carrier is primarily studied by examining the adsorption behaviors of three drugs.

• Periodical: Advanced Materials Research (Volumes 396-398)
• Pages: 330-335
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.396-398.330
• Online since: November 2011
• Authors: Ting Fan, Hui Zhang, Shao Huan Guo
• Keywords: Bioinorganic Nanohybrids, Bovine Serum Albumin (BSA), Drug, Layered Double Oxide

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