Simulation of Monomers Selection on Single-Molecular Copolymer Nano-Particles that Mimic Protein Folding

Wei Zhang

doi:10.4028/www.scientific.net/AMR.496.58

Paper Titles

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Structure Improvement on Dual Variable Gear Shaft of the Transmission for ZL50 Wheel Loader
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Electrochemical Sensing of L-Histidine Based on Structure-Switching Aptamer and Elongated Tetrahexaheral Gold Nanocrystals
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Simulation of Monomers Selection on Single-Molecular Copolymer Nano-Particles that Mimic Protein Folding
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Changes in Layer Properties and Physical Properties of Papers from Old Corrugated Container Fibres with PDADMAC/HEC Polyelectrolyte Multilayers
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 496Simulation of Monomers Selection on...

Simulation of Monomers Selection on Single-Molecular Copolymer Nano-Particles that Mimic Protein Folding

Abstract:

The synthesis of protein-like single molecular nano-particle can be simplified by use fewer but longer monomers, which correspond to several old short monomers. The selection of new long monomer subset is optimized and tested in HP model and other models. Results show 2-3 types new monomer are enough to build stable structure, and long monomers should include integer length of one helix, and with interlaced hydrophobic and polar side-chain, thus can form α-helix like structure.

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Periodical:

Advanced Materials Research (Volume 496)

Pages:

58-61

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.496.58

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Online since:

March 2012

Authors:

Wei Zhang

Keywords:

Foldamer, Nanoparticle, Simulation

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