The Fabricated Collagen-Based Nano-Hydroxyapatite/β-Tricalcium Phosphate Scaffolds

M. Ebrahimi; Naruporn Monmaturapoj; S. Suttapreyasri; P. Pripatnanont

doi:10.4028/www.scientific.net/AMR.506.57

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 506The Fabricated Collagen-Based...

The Fabricated Collagen-Based Nano-Hydroxyapatite/β-Tricalcium Phosphate Scaffolds

Abstract:

The biphasic calcium phosphate (BCP) concept was introduced to overcome disadvantages of single phase biomaterials. In this study, we prepared BCP from nanoHA and β-TCP that were synthesized via a solid state reaction. Three different ratios of pure BCP and collagen-based BCP scaffolds (%HA/%β-TCP; 30/70, 40/60 and 50/50) were produced using a polymeric sponge method. Physical and mechanical properties of all materials and scaffolds were investigated. XRD pattern proved the purity of each HA, β-TCP and BCP. SEM showed overall distribution of macropores (80-200 µm) with appropriate interconnected porosities. Total porosity of pure BCP (93% ± 2) was found to be higher than collagen-based BCP (85%± 3). It was observed that dimensional shrinkage of larger scaffold (39% ± 4) is lower than smaller one (42% ± 5) and scaffolds with higher HA (50%) ratio experienced greater shrinkage than those with higher β-TCP (70%) ratio (45% ±3 and 36% ±1 respectively). Mechanical properties of both groups tend to be very low and collagen coating had no influence on mechanical behavior. Further studies may improve the physical properties of these composite BCP.

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Periodical:

Advanced Materials Research (Volume 506)

Pages:

57-60

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.506.57

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Online since:

April 2012

Authors:

M. Ebrahimi, Naruporn Monmaturapoj, S. Suttapreyasri, P. Pripatnanont

Keywords:

BCP, Calcium Phosphate, Collagen, Nano-HA, Nano-β-TCP

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