Simultaneous Analysis of Cyromazine, Sulfonamides and Tetracyclines in Animal Wastewater and Soil Samples by Optimized LC-MS/MS

Abstract:

In order to predict the main species of veterinary drugs in the environment, cyromazine (CY), sulfonamides (SAs) and tetracyclines (TCs) were studied in animal wastewater and soil by liquid chromatography-tandem mass spectrometry. In the method, the reversed-phase column of C8 column, the HLB solid phase extraction column, the 0.1% formic acid acetonitrile-water solution mobile phase with gradient elution were used. The flow rate was 0.30 mL/min, the detection mode was multiple reaction monitoring (MRM) with positive ion electro spray ionization and the injection volume was 10 μL. The quantification limit of the method (MQL) was 5ng/L for CY, 25ng/L for SAs, and 50 ng/L TCs in animal wastewater samples. In soil samples, MQL was 25µg/kg for CY, 40µg/kg for SAs, and 50µg/kg for TCs. The correlation coefficient was higher than 0.99. Recoveries of CY, SAs and TCs at fortified levels were higher than 61%, with relative standard deviation of 0.84%-6.49%.

• Periodical: Advanced Materials Research (Volumes 518-523)
• Pages: 1611-1615
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.518-523.1611
• Online since: May 2012
• Authors: Rui Cheng Wei, Ming Cheng Shao, Ming Chen, Ran Wang
• Keywords: Cyromazine, LC-MS/MS, Residue, Sulfonamide, Tetracyclines (TCs)

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