Characterization and Antioxidant Activities of Polysaccharides from Fructus corni

Abstract:

The composition and antioxidant activities of two polysaccharides PFCAⅢ and PFCCⅠ, isolated from Fructus corni, have been investigated. The monosaccharide components of PFCAⅢ were found to be rhamnose, arabinose and glucose in a molar ratio of 13.74: 50.54: 35.72, whilst PFCCⅠ was found to consist of xylose and glucose in a molar ratio of 18.8: 81.2. The weight-average molecular weights of PFCAⅢ and PFCCⅠwere 1.74×10⁴ and 7.57×10⁴ respectively. The polysaccharides showed potential antioxidant activity by scavenging superoxide anion (O₂⁻∙) and hydroxyl free radicals (OH∙) and this was confirmed by their ability to inhibit oxidation of axunge and gingili. The concentrations required to scavenge 50% of hydroxyl free radicals (EC₅₀) of PFCAⅢ and PFCCⅠ were 430μg/ml and 80μg/ml respectively, and the extents of scavenging O₂⁻∙ by 500μg PFCAⅢ and PFCCⅠwere 15.9% and 68.0% respectively. The polysaccharide PFCCⅠ shows much more significant antioxidant activity than PFCAⅢ. PFCCⅠ was mainly linked with β(1→4)-D-glucosyl with side chains including 1-linked β-D-Glc, 1,6-linked β-D-Glc and 1,4-linked β-D-Xyl with branching points at C-6 of 1,4-linked Glc in main chain. It had the potential to be exploited by the food and pharmaceutical industries in the future with further research on this polysaccharide.

• Periodical: Advanced Materials Research (Volumes 560-561)
• Pages: 231-236
• DOI: https://doi.org/10.4028/www.scientific.net/AMR.560-561.231
• Online since: August 2012
• Authors: Ping Li, Zong Gang Mou, Geng Xiu Zheng, Run Yu Ma
• Keywords: Antioxidant Activity, Free Radical, Fructus corni, Isolation, Polysaccharide

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