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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 620Studies of Cell Growth on TiO2 Nanotubes

Studies of Cell Growth on TiO₂ Nanotubes

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Abstract:

The in vitro cell response was investigated on flat Ti surface vs nanostructured TiO₂ nanotube surface. The titanium dioxide nanotube layers were prepared by electrochemical anodization of Ti in ethylene glycol, 5 wt% NH₄F and 1ml H₂O₂. The nanotube layered structure and morphology were characterized using X-ray diffraction (XRD) and field emission scanning electron microscopy (FESEM). The diameter and the length of the nanotubes are found to increase with anodization voltage. Hs27 and breast cancer cell line MCF-7 were used for cell interaction studies. Different surfaces of titanium show variation in term of growth and viability of cells. Different cell type also show different cellular responses to these surfaces. Titanium nanotube with tube diameter 90 nm promoted normal cell adherence and spreading but killed the cancer cells. The detail of the observation is discussed thoroughly in this paper.

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Periodical:

Advanced Materials Research (Volume 620)

Pages:

325-329

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.620.325

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Online since:

December 2012

Authors:

Nur Hidayati Ahmad Barudin, Srimala Sreekantan, Ong Ming Thong, Lam Kit Lay

Keywords:

Anodization, Hs27, MCF-7, Scanning Electron Microscope (SEM), TiO₂ Nanotube

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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