Chemical Constituents and Anti-Acetylcholinesterase Activities of Dolomiaea wardii

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The chemical composition of the ethyl acetate and n-butanol extracts of Dolomiaea wardii has been reported for the first time in the present study and eight compounds were isolated and identified as corymbolone(1), encelin(2), 8-oxoargentone(3), betulinic acid(4), lupeol(5), 4-hydroxyacetophenone(6), sweroside(7), Laganoside(8). anti-acetylcholinesterase activity of 1-8 showed that compound 6 have weak inhibitory activity with IC50 value of 1.43 mM.

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Advanced Materials Research (Volumes 634-638)

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901-904

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January 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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