Simulation Study of Hemodynamics of Red Blood Cells in Stenotic Microvessels

Xiao Mei Jiang; Tong Wang; Zhong Wen Xing

doi:10.4028/www.scientific.net/AMR.647.321

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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 647Simulation Study of Hemodynamics of Red Blood...

Simulation Study of Hemodynamics of Red Blood Cells in Stenotic Microvessels

Abstract:

The shape and mechanical properties of abnormal red blood cells (RBCs) change considerably in comparison with healthy red blood cells (RBCs). In this paper, we perform numerical investigation of the hemodynamics of RBCs in microvessels with stenosis. Our model is based on an immersed boundary-fictitious domain method. We employ a spring model for representing deformability of RBC membrane. The proposed model successfully simulates complex motion and deformation of RBCs in micro scale flow. Our method would be helpful for further understandings of pathology of malaria and some other blood disorders.

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Periodical:

Advanced Materials Research (Volume 647)

Pages:

321-324

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.647.321

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Online since:

January 2013

Authors:

Xiao Mei Jiang, Tong Wang, Zhong Wen Xing

Keywords:

Malaria, Micro Circulation, Numerical Simulation, Red Blood Cell, Stenosis

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