Application of Smart Nanomaterials in Rheumatism Drug Delivery Systems

Article Preview

Abstract:

At present, more novel smart nanomaterials offering special responses towards some environmental stimuli have been used in the design and construction of rheumatism drug delivery systems to achieve a targeted drug release, thereby improving rheumatism drug efficacy and decreasing adverse rheumatism drug reaction. The current development of the application of pH, photo, thermo, enzyme and redox-responsive smart nanomaterials in rheumatism drug delivery systems was classifiedly reviewed.

You might also be interested in these eBooks

Info:

Periodical:

Pages:

141-144

Citation:

Online since:

February 2014

Authors:

Export:

Price:

Permissions CCC:

Permissions PLS:

Сopyright:

© 2014 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

* - Corresponding Author

[1] Wang D, Su Y, Jin C Y, et al. Supramolecular copolymer micelles based on the complementary multiple hydrogen bonds of nucleobases for drug delivery [J]. Biomacromo-lecules, 2011, 12(4): 1370-1379.

DOI: 10.1021/bm200155t

Google Scholar

[2] Zheng L S, Yang Y Q, Guo X D, et al. Mesoscopic simula-tions on the aggregation behavior of pH-responsive poly. Progress in Pharmaceutical Sciences meric micelles for drug delivery [J]. J Colloid Interf Sci, 2011, 363( 1) : 114-121.

DOI: 10.1016/j.jcis.2011.07.040

Google Scholar

[3] Zheng C, Xu J, Yao X P, et al. Polyphosphazene nanopar-ticles for cytoplasmic release of doxorubicin with improved cytotoxicity against Dox-resistant tumor cells [J].J Colloid Interf Sci, 2011, 355( 2) : 374-382.

DOI: 10.1016/j.jcis.2010.12.004

Google Scholar

[4] Jin Y G, Ren X, Wang W, et al. A 5-fluorouracil-loaded pH-responsive dendrimer nanocarrier for tumor targeting [J]. Int J Pharm, 2011, 420( 2) : 378-384.

DOI: 10.1016/j.ijpharm.2011.08.053

Google Scholar