Preparation and Characterizations of Electrospun Lactide-Based Polymeric Nanofibers

Abstract:

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Poly(L)lactide (PLLA), aliphatic polyester, and poly(LLA-co-DLLA) copolymers consisting of 2.5, 7.5, 50% of DLLA content were also synthesized. PLLA was successfully electrospun by using 15wt% solution in (1DMF:3CHCl3) mixed solvent. 2.5, 7.5, 50% P(LLA-co-DLLA) copolymers were then spun at 8, 10, and 15wt% concentration in a single chloroform solvent, respective. The lactide-based polymeric nanofibers were characterized by Scanning Electron Microscope (SEM). Smooth surface morphology was observed in nanofibers produced from PLLA and 50% P(LLA-co-DLLA) copolymer. However, surface porosity was observed in the corresponding fibers from 2.5 and 7.5% P(LLA-co-DLLA) copolymers. These nanofibers have high potential for wide range of applications such as filter media, nano-sensor, drug delivery and tissue scaffold, especially, those derived from 2.5 and 7.5% P(LLA-co-DLLA) copolymers which contain high degree of porosity.

Info:

Periodical:

Advanced Materials Research (Volumes 93-94)

Edited by:

S. Suttiruengwong and W. Sricharussin

Pages:

377-380

DOI:

10.4028/www.scientific.net/AMR.93-94.377

Citation:

C. Thammawong et al., "Preparation and Characterizations of Electrospun Lactide-Based Polymeric Nanofibers", Advanced Materials Research, Vols. 93-94, pp. 377-380, 2010

Online since:

January 2010

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Price:

$35.00

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