The Changes of the Corneal Tissue Structures and Biomechanical Properties in the Process of Cornea Post-Embryonic Development

Shuang Hao; Ai Jun Deng; Guo Hui Wang

doi:10.4028/www.scientific.net/AMR.934.3

Paper Titles

The Changes of the Corneal Tissue Structures and Biomechanical Properties in the Process of Cornea Post-Embryonic Development
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The Influence of Gyri and Sulci on the Skull-Brain Motion Based on Two Two-Dimensional Finite Element Models
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Development and Validation of a Finite Element Model of Human Cervical Spine Based on the Head-Neck Drop Test
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The Construction and Validation of a Finite Element Human Head Model for Skull Fracture
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Human Knee Dynamics Simulation and Application of Three Dimensional Finite Element Analysis
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Quantification Study on Bone Growth and Remodeling Adaptation Model Based on Experiment of Rapid-Growing Rats
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Analysis on the Differences of Body Composition and Maximal Oxygen Uptake between Sports and Non-Sports Male Students
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Soft Asphalt Pavement – Solution for Low-Volume Roads in Changing Climate and Economy
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HomeAdvanced Materials ResearchAdvanced Materials Research Vol. 934The Changes of the Corneal Tissue Structures and...

The Changes of the Corneal Tissue Structures and Biomechanical Properties in the Process of Cornea Post-Embryonic Development

Abstract:

To investigate the changes of corneal tissues morphological structure and biomechanical properties in different month age rabbits, the eyeballs of the 1 month, 2 month and 3 month-old-New Zealand white rabbits were obtained and getting the cornea tissues, and then measured the thickness of the cornea tissues. The first part of the corneal tissue was used to observe cornea structure with HE staining. The second part was used to observe collagen fibrils by electron microscope. The third part of the cornea tissues were cut into strips and used to test the elastic modulus of the cornea on Instron5544 tester. The thickness of the cornea was increased with month age. HE staining observation shows that the numbers of corneal fibroblasts were decreased and the fiber bundle increased with month age. Electron microscope observation shows that the diameters of collagen fibrils were increased at 2 and 3 month. Biomechanical experiment results reveal that cornea tissues elastic modulus was increased with month age. In the post-embryonic stages, the structure of cornea, the structure and number of collagen fiber, the number of corneal fibroblasts and the biomechanical properties of cornea were changed continually.

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Periodical:

Advanced Materials Research (Volume 934)

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3-7

DOI:

https://doi.org/10.4028/www.scientific.net/AMR.934.3

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Online since:

May 2014

Authors:

Shuang Hao, Ai Jun Deng, Guo Hui Wang*

Keywords:

Collagen, Cornea, Elasticity Modulus, Post-Embryonic Development

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