Comparative Study of Physicochemical Properties of Compound Danshen Powders

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Compare investigate physicochemical properties of coarse powder and four ultrafine powders of compound Danshen, and then to determinate particle size distribution for ultrafine powders. Surface morphology, bulk density , repose angle, the content of ethanol-soluble extract and water-soluble extract of compound Danshen powders were investigated. The content of salvianolic acid B, tanshinone IIA, tanshinone I, cryptotanshinone, notoginsenoside R1,ginsenoside Rg1 and ginsenoside Rb1 in compound Danshen powders were determined by HPLC. The results indicated that powder particle size decreased gradually with the extension of grinding time and finally into balance, but time was too long would make ultrafine powder easily gathered. Powder property results showed that ultrafine powders were worse liquidity and wettability. The contents in ultrafine powder D90≥38μm were increased with the decrease of the particle size, but when the particle size continued to decrease, the content would decline. Particle size of compond Danshen ultrafine powder should be controlled about 38 μm.

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300-304

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July 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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[1] F.S. Wu, L. Chen and Y.P. Wu. Superfine comminution of Glycyrrhiza uralensis roots by vibration mill. China Journal of Chinese Materia Medica, Vol. 30 (2005), pp.185-7.

Google Scholar

[2] ZH. Shu, G.F. Liu, M.H. Ma, et al. Study on the superfine comminution of traditional Chinese medicine. China Journal of Chinese Materia Medica, Vol. 29(2004), pp.823-7.

Google Scholar

[3] L. Chen, Y. Wu, L. Zhang. Superfine comminution technology and its application in the processing of Chinese traditional medicine. Journal of Chinese Medicinal Materials, Vol. 25(2002), pp.55-7.

Google Scholar

[4] Y.H. Liu, G. Du. The influence of superfine grinding of herbal active ingredient extraction yield. Chin Hosp Pharm J, Vol. 30 (2010), pp.66-69.

Google Scholar

[5] L.L. Shen, G. Du, J.J. Guo. The influence of active ingredient dissolution by Superfine grinding technology. Chin Hosp Pharm J, Vol. 31(2011), pp.1213-1214+1230.

Google Scholar

[6] W.G. Sun, Q. Zhen, F.Q. Liu, et al. The research progress of superfine grinding technology and powder characteristics. China Pharmaceuticals, Vol. 19(2009), pp.74-76.

Google Scholar

[7] X.Q. Chen, Y.H. Liu. The influence of efficacy of Traditional Chinese Medicine by superfine grinding technology. Central South Pharmacy, Vol. 9(2011), pp.295-299.

Google Scholar

[8] Ministry of Public Health of the People's Republic of China, Pharmacopoeia of the People's Republic of China, 2010, 1, 133. (In Chinese ).

Google Scholar