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CuO Nanoparticles: A Mild and Efficient Reusable Catalyst for the One-Pot Synthesis of 4-amino-5-pyrimidinecarbonitriles under Aqueous Conditions

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Abstract:

An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by three-component reaction of malononitrile, aldehydes and N-unsubstituted amidines, under aqueous conditions, using CuO nanoparticles as catalyst is reported. The protocol offers advantages in terms of higher yields, short reaction times, and mild reaction conditions, with reusability of the catalyst.

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Diffusion in Solids and Liquids VII View Preview

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Periodical:

Defect and Diffusion Forum (Volumes 326-328)

Pages:

372-376

DOI:

https://doi.org/10.4028/www.scientific.net/DDF.326-328.372

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Online since:

April 2012

Authors:

Seyed Javad Ahmadi, Sodeh Sadjadi, Morteza Hosseinpour

Keywords:

4-Amino-5-Pyrimidinecarbonitrile, CuO Nanoparticles, Supercritical Water Synthesis

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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