Development of Heart Simulator (Heart-S) on the Left Ventricle for Measuring the Blood Circulation during Cardiac Cycle

Abstract:

Heart is a complex structure which acts as a blood pump in mammal’s body. It is important to have detail study for the heart structure. Modeling of heart structure gives a better understanding and figure of the heart valve’s movement as well as the fluid flow movement in the heart chamber. In this paper, the heart simulator (Heart-S) on the left ventricle for measuring the blood circulation during cardiac cycle was proposed. Throughout the experimental modeling of heart valve structure by using rhythmic fluid flow in a closed chamber, the relationship between heart valve elasticity and heart valve angle position to the valve opening width were investigated. The main aspect of the present development is to provide a heart simulator apparatus to obtain data for development of artificial heart and for observing the blood circulation measurement. The result shows good agreement on valve elasticity and the velocity of the fluid from the vortex in the heart chamber can be found after the experiment. The novelty of this development is contributing to the study of the optimal vortex formation in the heart chamber and observe the blood circulation measurement.

• Periodical: Journal of Biomimetics, Biomaterials and Biomedical Engineering (Volume 36)
• Pages: 78-83
• DOI: https://doi.org/10.4028/www.scientific.net/JBBBE.36.78
• Online since: March 2018
• Authors: Loh Quo Liang, Kok Yin Hui, Nur Hazreen Mohd Hasni, Mohd Azrul Hisham Mohd Adib*
• Keywords: Blood Circulation, Cardiac Cycle, Heart Apparatus, Heart Simulator, Left Ventricle

References

[1] Abano, A., Kanda, K., Shibayama, T., Kamei, Y., Matsuda, T., 2007. Model generation interface for simulation of left ventricular motion, electronics, and communication in Japan, Part 2 90, 12.

DOI: 10.1002/ecjb.20425

[2] Bistoquet, A., Oshinski, J., Skrinjar, O., 2007. Left ventricular deformation recovery from cine MRI using an incompressible model. IEEE Transactions on Medical Imaging 26, 9, 1136-53.

DOI: 10.1109/tmi.2007.903693

[3] Doyle, M.G., Tavoularis, S., Bourgault, Y., 2011. Computation of blood flow in the left ventricle with fluid-structure interaction. Department of Mechanical Engineering, University of Ottawa 1-6.

DOI: 10.1615/tsfp7.580

[4] Mushtak AL-ATABI, Daniel, M.E., David, W.L., 2010. Computer and Experimental Modelling of Blood Flow through the Mitral Valve of the Heart. Journal of Biomechanical Science and Engineering, 5, 1.

DOI: 10.1299/jbse.5.78

[5] Adib, M.A.H.M., Hasni, N.H.M., 2017. Study the heart valve elasticity and optimal of vortex formation for blood circulation measurement on the left ventricle using the heart simulator (Heart-S) apparatus. 4th International Conference on Biomedical and Bioinformatics Engineering, ICBBE, 58-62.

DOI: 10.1145/3168776.3168786

[6] Domenichini, F., Querzoli, G., Cenedese, A., Pedrizzetti, G., 2007. Combined experimental and numerical analysis of the flow structure into the left ventricle. Journal of Biomechanics 40, 1988-(1994).

DOI: 10.1016/j.jbiomech.2006.09.024

[7] Hart, J.D., Peter, G.W.M., Schreurs, P.J.G., Baaijiens, F.P.T., 2000. A two dimensional fluid-structure interaction model of the aortic valve. Journal of Biomechanics 33, 1079-1088.

DOI: 10.1016/s0021-9290(00)00068-3

[8] Adib, M.A.H.M., Hasni, N.H.M., 2016. Degenerative vs rigidity on mitral valve leaflet using fluid structure interaction (FSI) model. Journal of Biomimetics, Biometarials, and Tissue Engineering 26, 60-65.

DOI: 10.4028/www.scientific.net/jbbbe.26.60

[9] Adib, M.A.H.M., Hasni, N.H.M., Razak, P.O.A., 2011. Analysis of echocardiography images using grid independent technique for patients with mitral valve problems (MVP). International Conference on Information Science and Application, ICISA, 1-5.

DOI: 10.1109/icisa.2011.5772385

[10] Adib, M.A.H.M., Mohd Hasni, N.H., Osman, K., Maskon, O., 2012. Analysis on the rigidity of mitral valve leaflet (MVL) and backflow problems during cardiac cycle. Journal of Biomimetics, Biometarials, and Tissue Engineering 13, 75-79.

DOI: 10.4028/www.scientific.net/jbbte.13.75

[11] Adib, M.A.H.M., Naim, F., Hasni, N.H.M., Osman, K., 2013. Prediction on behaviour of blood velocity and mitral leaflet displacement in the different shapes of heart valve during cardiac cycle. Journal of Biomimetics, Biometarials, and Tissue Engineering 17, 79-85.

DOI: 10.4028/www.scientific.net/jbbte.17.79

[12] Adib, M.A.H.M., Osman, K., Jong, R.P., 2010. Analysis of blood flows into the main artery via mitral valve: Fluid structure interaction model. International Conference on Science and Social Research, CSSR, 356-360.

DOI: 10.1109/cssr.2010.5773799

[13] Jong, R.P., Osman, K., Adib, M.A.H.M., 2012. Determination of correlation between backflow volume and mitral valve leaflet young modulus from two dimensional echocardiogram images. International Meeting of Advances in Thermofluids, IMAT, 606-611.

DOI: 10.1063/1.4704269