Biological Behaviour of Bonelike® Graft Implanted in the Tibia of Humans

Abstract:

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This paper reports the ability of Bonelike® to regenerate bone defected areas when implanted in the tibia of 3 patients (average age of 59 years) during a high tibial osteotomy (HTO) to treat medial compartment osteoarthritis of the knee. Bonelike® is a synthetic bone graft designed to mimic the inorganic composition of bone using a patent process that consists of liquid sintering hydroxyapatite in the presence of CaO-P2O5 based glass. The preliminary clinical evaluation performed showed that an intimate contact between new formed bone and Bonelike® was established (67±10 %), with no fibrous interface. Therefore, Bonelike® is a single-handedly viable osteoconductive synthetic grafting material as it has been demonstrated from the profiles of radiological, histological and scanning electron microscopy analyses for the six months implantation period.

Info:

Periodical:

Key Engineering Materials (Volumes 284-286)

Main Theme:

Edited by:

Panjian Li, Kai Zhang and Clifford W. Colwell, Jr.

Pages:

1041-1044

DOI:

10.4028/www.scientific.net/KEM.284-286.1041

Citation:

M. Gutierres et al., "Biological Behaviour of Bonelike® Graft Implanted in the Tibia of Humans", Key Engineering Materials, Vols. 284-286, pp. 1041-1044, 2005

Online since:

April 2005

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Price:

$35.00

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