Three RC slab specimens were designed and manufactured to investigate the fatigue behavior of RC slab retrofitted with carbon fiber mesh (CFM) and mortar. Among three slab specimens, two slabs were pre-loaded to introduce damage prior to the fatigue loading tests. Fatigue loading was applied to the top of slab maintaining 40% of the ultimate strength of specimen at 2Hz loading speed. The fatigue test was terminated when the loading cycle exceeded 1,000,000 cycles. From the test results, the effectiveness of the retrofitting using CFM was evaluated. Test result showed that the specimens retrofitted after either severe or light damages had very similar strength and stiffness to those of the specimens retrofitted without damage. It was found that the strength was even slightly improved in the specimen retrofitted with CFM.