Currently, there are adequate guidelines available for FRP retrofitting RC structures against static and seismic loads. However, there is still limited information on retrofitting RC structures against short-duration dynamic loading effects such as blast loading. Due to the increasing threat of terrorism in recent years, retrofitting of RC structures against blast loading is of paramount importance in structural engineering. In this paper, a dynamic model that is based on single-degree-of-freedom (SDOF) approach is developed for the analysis of the response of retrofitted fixed end supported RC slabs subjected to blast loads. A previously validated layered capacity analysis method is used to determine the yielded and ultimate blast resistant capacity of a cross-section of a RC slab which allows varying strain rates with time along the depth of the member. The corresponding deflections are determined by plastic hinge analysis. To simplify the calculation process, a tri-linear resistance-deflection function which consists of elastic, elasto-plastic and plastic region for fixed end supported RC slabs is converted to an equivalent bilinear function. This developed model can adequately predict the retrofitted members’ response to blast loading. It is then is used to conduct a parametric study to optimise the retrofitting of RC slabs subjected to blast loading by varying the quantity, material type and technique of retrofitting.