An investigation is reported on high-speed single-grain grinding for superalloy. The grooves’ morphology and area removal ratio, grinding force ratio, specific grinding force, and friction coefficient are studied. The area removal rate η increases with the grinding section area increasing. The plowing decreases with the grinding section area and grinding speed increase. Surface integrity can be improved under high speed and deep grinding. It is proved by experiments that the single-grain grinding friction coefficient decreases with the grinding speed increasing.