Fast Setting Pre-Mixed Calcium Phosphate Bone Cements Based on α-Tricalcium Phosphate

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Conventional calcium phosphate bone cements are self setting water based pastes. Recently pre-mixed calcium phosphate bone cements have been proposed that have non-aqueous fluid as liquid phase of the paste. Such cements thus only start setting reaction in contact with body fluids. In this work the properties (cohesion, compressive strength, phase composition) of pre-mixed calcium phosphate cements based on α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate are described. Properties of several cement compositions are examined and compared to properties of β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements. It was found that α-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements have higher compressive strength (10 - 15 MPa) than corresponding β-tricalcium phosphate and calcium dihydrogen phosphate monohydrate based cements (10 - 6 MPa). Out of examined cement paste liquids (glycerol, polyethylene glycol and polypropylene glycol) cements using glycerol as the liquid phase had higher compressive strength and are more cohesive.

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204-207

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March 2014

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© 2014 Trans Tech Publications Ltd. All Rights Reserved

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[1] S.V. Dorozhkin, Calcium Orthophosphate Cements and Concretes, J. Mater. Sci. 43 (2008) 3028-3057.

DOI: 10.1007/s10853-008-2527-z

Google Scholar

[2] Y. Shimada, L.C. Chow, S. Takagi, J. Tagami, Properties of injectable apatite-forming premixed cements, J. Res. Natl. Inst. Stan. 115 (2010) 233-241.

DOI: 10.6028/jres.115.017

Google Scholar

[3] B. Han, P. -W. Ma, L. -L. Zhang, Y. -J. Yin, K. -D. Yao, F. -J. Zhang, Y. -D. Zhang, X. -L. Li, W. Nie, β-TCP/MCPM-based premixed calcium phosphate cements, Acta Biomater. 5 (2009) 3165-3177.

DOI: 10.1016/j.actbio.2009.04.024

Google Scholar

[4] S. Takagi, L.C. Chow, S. Hirayama, A. Sugawara, Premixed Calcium-Phosphate Cement Pastes, J. Biomed. Mater. Res. B 67 (2003) 689-696.

DOI: 10.1002/jbm.b.10065

Google Scholar

[5] Z. Irbe, L. Vecbiskena, L. Berzina-Cimdina, Setting properties of brushite and hydroxyapatite compound cements, Adv. Mat. Res. 222 (2011) 239-242.

DOI: 10.4028/www.scientific.net/amr.222.239

Google Scholar