Effects of Surface Properties of Montmorillonite for their Cytocompatibility

Abstract:

We modified the surface of organically modified montmorillonite (OMMT) with the carboxyl group using the silane coupling reaction and assessed its characteristics and cytocompatibility. Scanning electron microscope observations show that while the size and morphology of the obtained OMMT (OMMT-COOH) was unchanged, the surface of OMMT-COOH was coarser than that of OMMT. Fourier transform infrared spectra showed characteristic strong peaks at 1210 and 1630 cm⁻¹, corresponding to the peaks of the carboxyl group. X-ray diffraction analysis showed that the diffraction peak of OMMT-COOH corresponding to the (001) reflection was located at higher a 2θ value than that of OMMT. Results of the proliferation ratio and cell viability measurements indicated that the OMMT-COOH cytocompatibility is higher than that of OMMT. Based on these results, we conclude that cytocompatibility of montmorillonite would be improved by tuning the properties of the surface.

• Periodical: Key Engineering Materials (Volume 696)
• Pages: 80-84
• DOI: https://doi.org/10.4028/www.scientific.net/KEM.696.80
• Online since: May 2016
• Authors: Ko Nakanishi*, Shigeaki Abe, Shuichi Yamagata, Yasuhiro Yoshida, Junichiro Iida
• Keywords: Carboxylation, Cytocompatibility, Montmorillonite

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