The conservation of historic stone sculptures and buildings is a focus of research. But there are no completely satisfying protective materials until now. In this paper, a conservative film of apatite has been prepared on the surface-modified marble stone by using a solution of CaCl2 and (NH4)2HPO4 as the precursor through a biomimetic method. The prepared material was characterized by some instruments. Its performances were also evaluated by its ability to consolidate, resist soil and acid. The obtained results indicate that the conservative effects are satisfying and the biomimetic synthesis should represent a new prospective in stone conservation.