Investigation of Structural and Antifungal Behaviors of Nano-Sized Anatase Titanium Dioxide Synthesized by Co-Precipitation Route

Abstract:

Nowadays, the application of nano-sized anatase titanium dioxide particles becomes one of the essential research focuses by many experts, especially for biomedical applications. In this work, we report the utilization of coprecipitation route in preparing nano-sized anatase titanium dioxide as an antifungal agent. The data analysis for the XRD data of the titanium dioxide particles showed that the sample crystallized with anatase structure and sized in the nanometric size of 13.30 nm. The particle size obtained from Scherrer’s analysis of the XRD data was quite similar to the particle size obtained from electron microscopy investigation. Furthermore, the small-angle scattering data presented that the anatase titanium dioxide constructed a 3-dimensional structure with a compact structure originating from the fractal dimension value of approximately 3. The functional groups of the nano-sized anatase titanium dioxide were traced in the wavelength range of 500-1500 cm^-1 showing the presence of Ti-O bonding. Interestingly, the prepared sample in this experiment exhibited an excellent performance as an antifungal agent represented by inhibition zone diameter of 3.59 mm.

• Periodical: Materials Science Forum (Volume 966)
• Pages: 181-188
• DOI: https://doi.org/10.4028/www.scientific.net/MSF.966.181
• Online since: August 2019
• Authors: Ahmad Taufiq*, Deny Arista, Sunaryono Sunaryono, Rosy Eko Saputro, Nurul Hidayat, Siriwat Soontaranon, Erfan Handoko, Darminto Darminto
• Keywords: Antifungal Agent, Nanosized Particle, Structure, Titanium Dioxide

References

[1] Y. Hao, X. Cao, C. Ma, Z. Zhang, N. Zhao, A. Ali, T. Hou, Z. Xiang, J. Zhuang, S. Wu, B. Xing, Z. Zhang, Y. Rui, Potential Applications and Antifungal Activities of Engineered Nanomaterials against Gray Mold Disease Agent Botrytis cinerea on Rose Petals, Frontiers in Plant Science. 8 (2017) 1-9.

DOI: 10.3389/fpls.2017.01332

[2] D.D. Cibim, M.T. Saito, P.A. Giovani, A.F.S. Borges, V.G.A. Pecorari, O.P. Gomes, P.N. Lisboa-Filho, F.H. Nociti-Junior, R.M. Puppin-Rontani, K.R. Kantovitz, Novel Nanotechnology of TiO2 Improves Physical-Chemical and Biological Properties of Glass Ionomer Cement, International Journal of Biomaterials. 7123919 (2017) 1-11.

DOI: 10.1155/2017/7123919

[3] A. Di Paola, M. Bellardita, L. Palmisano, Brookite, the Least Known TiO2 Photocatalyst, Catalysts. 3 (2013) 36–73.

DOI: 10.3390/catal3010036

[4] L.K. Preethi, T. Mathews, M. Nand, S.N. Jha, C.S. Gopinath, S. Dash, Band alignment and charge transfer pathway in three phase anatase-rutile-brookite TiO2 nanotubes: An efficient photocatalyst for water splitting, Applied Catalysis B: Environmental. 218 (2017) 9–19.

DOI: 10.1016/j.apcatb.2017.06.033

[5] S. El-Sherbiny, F. Morsy, M. Samir, O.A. Fouad, Synthesis, characterization and application of TiO2 nanopowders as special paper coating pigment, Applied Nanoscience. 4 (2014) 305–313.

DOI: 10.1007/s13204-013-0196-y

[6] C. Dette, M.A. Pérez-Osorio, C.S. Kley, P. Punke, C.E. Patrick, P. Jacobson, F. Giustino, S.J. Jung, K. Kern, TiO2 Anatase with a Bandgap in the Visible Region, Nano Lett. 14 (2014) 6533–6538.

DOI: 10.1021/nl503131s

[7] R. Kaplan, B. Erjavec, G. Dražić, J. Grdadolnik, A. Pintar, Simple synthesis of anatase/rutile/brookite TiO2 nanocomposite with superior mineralization potential for photocatalytic degradation of water pollutants, Applied Catalysis B: Environmental. 181 (2016) 465–474.

DOI: 10.1016/j.apcatb.2015.08.027

[8] F. Haghighi, S. Roudbar Mohammadi, P. Mohammadi, S. Hosseinkhani, R. Shipour, Antifungal activity of TiO2 nanoparticles and EDTA on Candida albicans biofilms, Infection, Epidemiology and Microbiology. 1 (2013) 33–38.

[9] E. Larkin, C. Hager, J. Chandra, P.K. Mukherjee, M. Retuerto, I. Salem, L. Long, N. Isham, L. Kovanda, K. Borroto-Esoda, The emerging pathogen Candida auris: growth phenotype, virulence factors, activity of antifungals, and effect of SCY-078, a novel glucan synthesis inhibitor, on growth morphology and biofilm formation, Antimicrobial Agents and Chemotherapy. 61 (2017) e02396-16.

DOI: 10.1128/aac.02396-16

[10] D.-H. Lee, B. Swain, D. Shin, N.-K. Ahn, J.-R. Park, K.-S. Park, One-pot wet chemical synthesis of fluorine-containing TiO2 nanoparticles with enhanced photocatalytic activity, Materials Research Bulletin. 109 (2019) 227–232.

DOI: 10.1016/j.materresbull.2018.09.027

[11] S.G. Ullattil, P. Periyat, Microwave-power induced green synthesis of randomly oriented mesoporous anatase TiO2 nanoparticles for efficient dye sensitized solar cells, Solar Energy. 147 (2017) 99–105.

DOI: 10.1016/j.solener.2017.03.039

[12] K.D. Parikh, J.H. Joshi, M.J. Joshi, Influence of organic dopants (L-alanine and L-arginine) on structural, spectroscopic and thermal properties of ammonium dihydrogen phosphate crystal, Materials Science-Poland. 35 (2017) 632–638.

DOI: 10.1515/msp-2017-0067

[13] M. Kardanzadeh, I. Kazeminezhad, S. Mosivand, Electro-synthesis and characterization of TiO2 nanoparticles and their application in removal of congo red from water without UV radiation, Ceramics International. 44 (2018) 5652–5659.

DOI: 10.1016/j.ceramint.2017.12.214

[14] M. Ojeda, B. Chen, D.Y. Leung, J. Xuan, H. Wang, A hydrogel template synthesis of TiO2 nanoparticles for aluminium-ion batteries, Energy Procedia. 105 (2017) 3997–4002.

DOI: 10.1016/j.egypro.2017.03.836

[15] J. Jia, H. Yamamoto, T. Okajima, Y. Shigesato, On the Crystal Structural Control of Sputtered TiO2 Thin Films, Nanoscale Research Letters. 11 (2016) 324 1-9.

DOI: 10.1186/s11671-016-1531-5

[16] D. Ren, J. Li, Y. Bao, Z. Wu, S. He, A. Wang, F. Guo, Y. Chen, Low-temperature synthesis of flower-like ZnO microstructures supported on TiO2 thin films as efficient antifungal coatings for bamboo protection under dark conditions, Colloids and Surfaces A: Physicochemical and Engineering Aspects. 555 (2018) 381–388.

DOI: 10.1016/j.colsurfa.2018.07.015

[17] S. Yu, J. Liu, Y. Zhou, R.D. Webster, X. Yan, Effect of synthesis method on the nanostructure and solar-driven photocatalytic properties of TiO2-CuS composites, ACS Sustainable Chemistry & Engineering. 5 (2017) 1347–1357.

DOI: 10.1021/acssuschemeng.6b01769

[18] K.G. Rao, C.H. Ashok, K.V. Rao, C.S. Chakra, V. Rajendar, Synthesis of TiO2 nanoparticles from orange fruit waste, Synthesis. 1 (2015) 82–90.

[19] V. Vetrivel, K. Rajendran, V. Kalaiselvi, Synthesis and characterization of pure titanium dioxide nanoparticles by sol-gel method, Int. J. ChemTech Res. 7 (2015) 1090–1097.

[20] M. Sundrarajan, K. Bama, M. Bhavani, S. Jegatheeswaran, S. Ambika, A. Sangili, P. Nithya, R. Sumathi, Obtaining titanium dioxide nanoparticles with spherical shape and antimicrobial properties using M. citrifolia leaves extract by hydrothermal method, Journal of Photochemistry and Photobiology B: Biology. 171 (2017) 117–124.

DOI: 10.1016/j.jphotobiol.2017.05.003

[21] A. Hassani, A. Khataee, S. Karaca, C. Karaca, P. Gholami, Sonocatalytic degradation of ciprofloxacin using synthesized TiO2 nanoparticles on montmorillonite, Ultrasonics Sonochemistry. 35 (2017) 251–262.

DOI: 10.1016/j.ultsonch.2016.09.027

[22] L. Mino, A. Zecchina, G. Martra, A.M. Rossi, G. Spoto, A surface science approach to TiO2 P25 photocatalysis: An in situ FTIR study of phenol photodegradation at controlled water coverages from sub-monolayer to multilayer, Applied Catalysis B: Environmental. 196 (2016) 135–141.

DOI: 10.1016/j.apcatb.2016.05.029

[23] Y. Ide, N. Inami, H. Hattori, K. Saito, M. Sohmiya, N. Tsunoji, K. Komaguchi, T. Sano, Y. Bando, D. Golberg, Remarkable charge separation and photocatalytic efficiency enhancement through interconnection of TiO2 nanoparticles by hydrothermal treatment, Angewandte Chemie International Edition. 55 (2016) 3600–3605.

DOI: 10.1002/anie.201510000

[24] A. Taufiq, Sunaryono, E.G. Rachman Putra, A. Okazawa, I. Watanabe, N. Kojima, S. Pratapa, Darminto, Nanoscale Clustering and Magnetic Properties of MnxFe3-xO4 Particles Prepared from Natural Magnetite, Journal of Superconductivity and Novel Magnetism. 28 (2015) 2855–2863.

DOI: 10.1007/s10948-015-3111-9

[25] A. Taufiq, Sunaryono, N. Hidayat, A. Hidayat, E.G.R. Putra, A. Okazawa, I. Watanabe, N. Kojima, S. Pratapa, Darminto, Studies on Nanostructure and Magnetic Behaviors of Mn-Doped Black Iron Oxide Magnetic Fluids Synthesized from Iron Sand, NANO. 12 (2017) 1750110.

DOI: 10.1142/s1793292017501107

[26] A. Sotto, A. Boromand, R. Zhang, P. Luis, J.M. Arsuaga, J. Kim, B. Van der Bruggen, Effect of nanoparticle aggregation at low concentrations of TiO2 on the hydrophilicity, morphology, and fouling resistance of PES–TiO2 membranes, Journal of Colloid and Interface Science. 363 (2011) 540–550.

DOI: 10.1016/j.jcis.2011.07.089

[27] P. Apopei, C. Catrinescu, C. Teodosiu, A. Ungureanu, S. Royer, Selective dissolution of TiO2 crystalline phases: Physicochemical characterization and photocatalytic activity, Comptes Rendus Chimie. 21 (2018) 382–390.

DOI: 10.1016/j.crci.2017.02.006

[28] X. Hu, Y. Li, J. Tian, H. Yang, H. Cui, Highly efficient full solar spectrum (UV-vis-NIR) photocatalytic performance of Ag2S quantum dot/TiO2 nanobelt heterostructures, Journal of Industrial and Engineering Chemistry. 45 (2017) 189–196.

DOI: 10.1016/j.jiec.2016.09.022

[29] H.A. Foster, I.B. Ditta, S. Varghese, A. Steele, Photocatalytic disinfection using titanium dioxide: spectrum and mechanism of antimicrobial activity, Appl. Microbiol. Biotechnol. 90 (2011) 1847–1868.

DOI: 10.1007/s00253-011-3213-7

[30] T.J. Battin, F. v.d. Kammer, A. Weilhartner, S. Ottofuelling, T. Hofmann, Nanostructured TiO2: Transport Behavior and Effects on Aquatic Microbial Communities under Environmental Conditions, Environ. Sci. Technol. 43 (2009) 8098–8104.

DOI: 10.1021/es9017046

[31] K. Gopinath, S. Kumaraguru, K. Bhakyaraj, S. Thirumal, A. Arumugam, Eco-friendly synthesis of TiO2, Au and Pt doped TiO2 nanoparticles for dye sensitized solar cell applications and evaluation of toxicity, Superlattices and Microstructures. 92 (2016) 100–110.

DOI: 10.1016/j.spmi.2016.02.012

[32] C. Fonseca, A. Ochoa, M.T. Ulloa, E. Alvarez, D. Canales, P.A. Zapata, Poly (lactic acid)/TiO2 nanocomposites as alternative biocidal and antifungal materials, Materials Science and Engineering: C. 57 (2015) 314–320.

DOI: 10.1016/j.msec.2015.07.069