Novel pH-Responsive Triply Hydrophilic Block Copolymer with Reversible Micellization Property
Stimuli-responsive water-soluble and amphiphilic polymers have attracted much attention because their micelles can be produced or destroyed by changing the temperatute, pH, ionic strength, and solvent polarity. In this work, a triply hydrophilic block copolymer of poly (ethylene glycol) and poly (methacrylic acid-co-dimethylamine ethyl methacrylate) [PEO-P(MAA-co-DMAEMA)] was synthesized and characterized. The copolymer system is believed to have the potential for drug delivery applications due to the biocompatibility of MAA and DMAEMA.
Yuan Ming Huang
X. D. Tang et al., "Novel pH-Responsive Triply Hydrophilic Block Copolymer with Reversible Micellization Property", Solid State Phenomena, Vols. 181-182, pp. 88-91, 2012