Novel pH-Responsive Triply Hydrophilic Block Copolymer with Reversible Micellization Property

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Abstract:

Stimuli-responsive water-soluble and amphiphilic polymers have attracted much attention because their micelles can be produced or destroyed by changing the temperatute, pH, ionic strength, and solvent polarity. In this work, a triply hydrophilic block copolymer of poly (ethylene glycol) and poly (methacrylic acid-co-dimethylamine ethyl methacrylate) [PEO-P(MAA-co-DMAEMA)] was synthesized and characterized. The copolymer system is believed to have the potential for drug delivery applications due to the biocompatibility of MAA and DMAEMA.

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Periodical:

Solid State Phenomena (Volumes 181-182)

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88-91

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November 2011

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© 2012 Trans Tech Publications Ltd. All Rights Reserved

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DOI: 10.1021/ma980689g

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