Combined Photodynamic Thermochemotherapy of Glial Tumors Controlled by MRI and Electronic Sensor

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Abstract:

As a result of consecutive intravenous injections of combination from 0.05 up to 1.0 ml 1.0-10 % sol Dextran-ferrite (DF), and 0.001-0.02 ml Magnevist contrast-enhansend (CE) MRI, have reduced to 4 days time of early visualization CE MRI of proliferation centres of glial tumor. Electron-touch mapping DF in a tumor and a liver have defined size of a ratio of contents DF in a tumor to contents DF in a liver ≥ 100 at which combined photodynamic magneto-thermochemotherapy, was preferable and have increased life span of rats with glioma C6 (GC6) up to 166% and at glioblastoma 101/8 (GB 101/8) up to 74%.

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Solid State Phenomena (Volumes 233-234)

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757-760

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July 2015

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© 2015 Trans Tech Publications Ltd. All Rights Reserved

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[1] K. Maier-Hauff, F. Ulrich, D. Nestler, et al., J. Neurooncol. 103 (2011) 317-324.

Google Scholar

[2] F. A Howe, S.J. Barton, S.A. Cudlip, et al., Magn. Resonans Med. 49 (2003) 223-232.

Google Scholar

[3] M.V. Gulyaev, N.V. Anisimov, et al., Rus. Technologies of living systems. 10 (2013) 35-40.

Google Scholar

[4] N.A. Brusentsov, Rus. J. Gen. Chem. 83 (2013) 2548-2558. doi 10. 1134/S1070363213120530.

Google Scholar

[5] N.A. Brusentsov, Yu.A. Pirogov, et al., Solid State Phenomena. 190 (2012) 717-720.

Google Scholar

[6] N.A. Brusentsov, V.A. Polyanskiy, Y. Pirogov et al., Pharm. Chem. J. 44 (2010) 291-295.

Google Scholar

[7] U. O. Häfeli, K. Gilmour, A. Zhou, et al., J. Magn. Magn. Mater. 311 (2007) 323-329.

Google Scholar

[8] S. Laurent, S. Dutz, U.O. Häfeli, et al., Advances Colloid Interface Sci. 166 (2011) 8-23.

Google Scholar

[9] I. Hilger, Int. J. Hyperthermia. 29 (2013) 828–834.

Google Scholar

[10] A.A. Petryk, A.J. Giustini, R.E. Gottesman, et al., Int. J. Hyperthermia 29 (2013) 845-851.

Google Scholar

[11] C. Tassa, S.Y. Shaw, and R. Weissleder Acc. Chem. Res. 44 (2011) 842–852.

Google Scholar

[12] B.K. Kwak, J.H. Geschwind, P.P. Rao et al., Advances in Molecular Imaging, 1 (2011), 24-32.

Google Scholar

[13] P.I. Nikitin, P.M. Vetoshko. Patents RU 2166751, RU 2177611 (2000), EP 1262766, EP 2120041 (2001).

Google Scholar

[14] M. P. Nikitin, P. Vetoshko et al., J. Magn. Magn. Mater. 321 (2009) 1658-1661.

Google Scholar

[15] M. Nikitin, M. Yuriev et al., AIP Conf. Proc. 1311 (2010) 452-457.

Google Scholar

[16] O. Rebrova, The Medicine Statistic's Analysis Facts, Media Sphere, Moscow, (2002).

Google Scholar