Chiral Separation of Amino Acid Derivatives by Molecular Imprinting Technique

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Abstract:

Molecularly imprinted polymers, based on the surface-modified silica gel, were prepared with silylanized silica gel as a carrier, acrylamide as functional monomer, ethylene dimethacrylate (EDMA) as crosslinker and Boc-L-phenylalanine as the template molecule. The results of HPLC shows that the imprinted polymers have good specific recognition of Boc-L-phenylalanine. The baseline separation of Boc-phenylalanine enantiomer was achieved in 20 min, the resolution was 1.84 and the maximum adsorption capacity was 6788 mg g-1.

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Periodical:

Advanced Materials Research (Volumes 239-242)

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2545-2548

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May 2011

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© 2011 Trans Tech Publications Ltd. All Rights Reserved

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