This paper introduces the detection and evaluation results of a diseased highway bridge using nondestructive testing method according to Chinese specification. The bridge was firstly inspected to judge the apparent diseases of deck pavement and upper stuructures. The end-span prestressed concrete hollow slabs were detected by nondestructive testing for rebound strength and carbonation depth of concrete, corrosion and concrete cover of prestressed bars and cracks at bottom surface of the slabs. The synthetic judgement is given out based on the inspecting and testing results. Some measures are proposed for strengthening the bridge such as bonding steel plates and carbon fiber reinforced polymer laminates on the bottom surface of diseased slabs, recasting concrete of slab joints and renewing asphalt concrete of deck pavement.