Reconfigurable Manufacturing Systems (RMS) have the potential to emerge as a cost effective solution that will help manufacturing organizations to stay competitive in an environment where product mix changes frequently and product life cycles are getting shorter. Reconfigurable Manufacturing Systems can achieve this as they are designed for quick changes in its configuration, as well as software and hardware components. This not only helps in accommodating production capacity but also production of new variety of products and introduction of new product within part family. However, the configurations have a significant impact on the productivity and reliability of the machines and the manufacturing system. In the present paper, the main objective is to present a framework consisting of Maintenance plan to be followed for the reconfigured machine, Reliability of the reconfigured machine, Quality of the product obtained. This framework can form as the basic idea and a link between maintenance, reliability and quality issues.