A comprehensive numerical study on the natural convection in a hydrodynamically anisotropic as well as isotropic porous enclosure is presented, flow is induced by non uniform sinusoidal heating of the right wall of the enclosure. The principal directions of the permeability tensor has been taken oblique to the gravity vector. The spectral Element method has been adopted to solve numerically the governing differential equations by using the vorticity-stream-function approach. The results are presented in terms of stream function, temperature profile and Nusselt number. The result show that the maximum heat transfer takes place at y = 1.5 when N is odd.. Also, increasing media permeability, by changing K* = 1 to K* = 0.2, increases heat transfer rate at below and above right corner of the enclosure. Furthermore, for the all values of N, profiles of local Nusselt number (Nuy) in isotropic as well as anisotropic media are similar, but for even values of N differ slightly at N = 2.. In particular the present analysis shows that, different periodicity (N) of temperature boundary condition has the significant effect on the flow pattern and consequently on the local heat transfer phenomena.