Helicid-Loaded Zein Microparticles Prepared Using Electrohydrodynamic Atomization

Deng Guang Yu; Xia Wang; Yao Zu Liao; Ying Li; Wei Qian; Xiao Yan Li

doi:10.4028/www.scientific.net/AMM.164.487

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 164Helicid-Loaded Zein Microparticles Prepared Using...

Helicid-Loaded Zein Microparticles Prepared Using Electrohydrodynamic Atomization

Abstract:

An electrohydrodynamic atomization (EHDA) process was exploited to prepare helicid-loaded zein microparticles. SEM observations showed that all the particles prepared under varied voltages were round and solid with their sizes gradually decreased from 3.4 ± 1.7 to 1.1 ± 0.5 μm as the applied voltages rose from 6 to 18 kV. Wide-angle X-ray diffraction analyses demonstrated that helicid had been totally converted into an amorphous state in the zein matrix microparticles. Attenuated total reflectance Fourier transform infrared analysis disclosed that the hydrogen bonding presented between helicid and zein molecules. In vitro dissolution tests verified that the microparticles were able to provide a fine sustained drug release profile. The present study provides an easy way to develop novel biomaterials for drug delivery and for providing sustained drug release profiles.

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Periodical:

Applied Mechanics and Materials (Volume 164)

Pages:

487-491

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.164.487

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Online since:

April 2012

Authors:

Deng Guang Yu, Xia Wang, Yao Zu Liao, Ying Li, Wei Qian, Xiao Yan Li

Keywords:

Biomaterial, Electrohydrodynamic Atomization, Helicid, Microparticles, Zein

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References

[1] W. Nie, D.G. Yu, C. Branford-White, X.X. Shen and L.M. Zhu: Mater. Res. Innov. Vol. 14 (2012), p.16.

Google Scholar

[2] O.C. Farokhzad and R. Langer: ACS Nano: Vol. 16 (2009), p.3.

Google Scholar

[3] D.G. Yu, J.H. Yang, X. Wang and F Tian: Nanotechnology Vol. 23 (2012), p.105606.

Google Scholar

[4] D.G. Yu, G.R. Williams, J.H. Yang, X. Wang, J.M. Yang and X.Y. Li: J. Mater. Chem. Vol. 21 (2011), p.15957.

Google Scholar

[5] D.G. Yu, G.R. Williams, L.D. Gao, S.W.A. Bligh, J.H. Yang and X. Wang: Colloid Surface A Vol. 396 (2012), p.161.

Google Scholar

[6] D.G. Yu, C. Branford-White, S.W.A. Bligh, K. White, N.P. Chatterton and L.M. Zhu: Macromol. Rapid Commun. Vol. 32 (2011), p.744.

DOI: 10.1002/marc.201100049

Google Scholar

[7] D.G. Yu, L.M. Zhu, C. Branford-White, S.W.A. Bligh and K. White: Chem. Commun. Vol. 47 (2011), p.1216.

Google Scholar

[8] D.G. Yu, C. Branford-White, N.P. Chatterton, K. White, L.M. Zhu, X.X. Shen and W. Nie, Macromolecules Vol. 43(2010), p.10743.

DOI: 10.1021/ma1024363

Google Scholar

[9] D.G. Yu, K. White, J.H. Yang, X. Wang, W. Qian and Y. Li: Mater. Lett. Vol. 67 (2012), p.78.

Google Scholar

[10] D.G. Yu, N.P. Chatterton, J.H. Yang, X. Wang, Y.Z. Liao: Macromol. Mater. Eng. DOI: 10. 1002/mame. 201100258 (2012).

Google Scholar

[11] D.G. Yu, D.G. Yu, L.D. Gao, K. White, C. Brandford-White, W.Y. Lu and L. M. Zhu: Pharm. Res. Vol. 27 (2010), p.2466.

Google Scholar