Effects of glue spread, adhesive kind and curing agent ratio and FRP (Fiber Reinforced Plastic) on stiffness of wood-FRP bonding interface were investigated. Two different kinds of epoxy resin and one kind of curing agent were used to bond wood-wood and wood-FRP samples with three different glue spread. Shear modulus of samples were measured by compression shear test to represent the stiffness of bonding interface. The results indicated that curing agent ratio and glue spread had significant effect on stiffness of wood-wood and wood-FRP bonding interfaces. In addition, the stiffness of wood-FRP interface was less than that of wood-wood interface.