tHcy Detected by High Performance Liquid Chromatography will be a Dangerous Factor for the Invasion of Occlusive Vascular Disease

Abstract:

Objective:To study the clinical application of high performance liquid chromatography（HPLC)、Radioimmunodetection and Automatic biochemical Analyzer on the detection of plasma total homocysteine(tHcy)、folic acid（FA）、VitB12、Triglyceride（TG）、total cholesterol(Ch)、high density lipoprotein cholesferol(HDL-C) and low density lipoprotein cholestorol(LDL-C).To manifest mechanism of the increasing of tHcy leading to diabetic retinopathy.Methods:The levels of plasma tHcy 、folic acid、VitB12、blood sugar、 blood pressure and blood lipid were detected by the instrumentations above in diabetic retinopathy cases.Results:The levels of plasma tHcy in diabetic retinopathy group were much higher than that in the control group.Conclusions:We discovered biomarkers of diabetic retinopathy.HPLC method can be used well for the detection of tHcy.

• Periodical: Applied Mechanics and Materials (Volumes 268-270)
• Pages: 1644-1647
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.268-270.1644
• Online since: December 2012
• Authors: Hong Yan Zhou, Wen Song Zhang, Ji Long Hao, Shuang Wang
• Keywords: Diabetic Retinopathy, High Performance Liquid Chromatography (HPLC), Plasma Total Homocysteine

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