A Novel and Experimental Design for Mechanical Ventilation with Optimal Spontaneous Flow Pattern and WOB Feedback Control

Abstract:

In this study, we proposed an innovative design for mechanical ventilation by applying the previously implemented optimal respiratory control simulator as the controller of an experimental ventilation device. Instead of providing a fixed airflow pattern, an optimal spontaneous flow pattern was optimized by the simulator based on patient’s estimated respiratory mechanics and was applied to drive a ventilation device. We also implemented an experimental ventilation control system, including the simulator, a ventilation device, an artificial lung, and a feedback control mechanism to attain minimum work of breathing during mechanical ventilation. The experiments were elaborated to verify that once patient’s respiratory physiology was significant changed, the breathing signals and measured respiratory mechanics were instantaneously monitored, and the optimization process was renewed by the simulator under the feedback control strategy.

• Periodical: Applied Mechanics and Materials (Volumes 284-287)
• Pages: 2189-2193
• DOI: https://doi.org/10.4028/www.scientific.net/AMM.284-287.2189
• Online since: January 2013
• Authors: Shyan Lung Lin, San Shan Hung, Ching Kun Chen, Hsing Cheng Chang
• Keywords: Mechanical Ventilation, Optimal Respiratory Control Simulator, Respiratory Mechanics, Spontaneous Airflow, Work of Breathing

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