Statistical Optimization of Synthesis of β-Methylhydrogen Itaconate

Jing Zhao

doi:10.4028/www.scientific.net/AMM.312.341

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vol. 312Statistical Optimization of Synthesis of...

Statistical Optimization of Synthesis of β-Methylhydrogen Itaconate

Abstract:

β-Methylhydrogen itaconate was synthesized with itaconic acid and methyl alcohol and using benzoyl chloride as catalyst. The important variables (reaction temperature, reaction time and substrate mole ratio) were optimized by Box-Behnken central composite design under response surface methodology. The statistical analysis showed that the optimum reaction conditions (temperature 58.98 °C, time 0.5 h and substrate molar ratio 3.71) led to a maximum yield (99.2%).

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Periodical:

Applied Mechanics and Materials (Volume 312)

Pages:

341-344

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.312.341

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Online since:

February 2013

Authors:

Jing Zhao

Keywords:

Model, Optimization, Statistical Experimental Designs, β-Methylhydrogen Itaconate

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