Determination of Eight Parabens in Water-Based Food Simulants Migrated from Antibacterial Plastic Packaging by LC/MS/MS

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A method based on reversed-phase liquid chromatography-tandem mass spectrometry (LC/MS/MS) combined with solid phase extraction (SPE) was developed and validated for qualitative and quantitative detection of eight parabens in three types of water-based food simulants including distilled water, 3% acetic acid, 10% alcohol. Detection limits of eight parabens after SPE procedure were 0.005-0.010 μg/L in distilled water, 0.006-0.015 μg/L in 3% acetic acid and 0.005-0.017 μg/L in 10% alcohol. The relative standard deviations (RSDs) were in the range of 1.90-8.48% for distilled wsater, 1.01-3.73% for 3% acetic acid and 5.78-12.97% for 10% alcohol. The method could make a complement for detecting parabens migrated to food and feeds.

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1993-1997

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July 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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