Real-Time Monitoring of Anthocyanidin-Zeolite Complex Exposed to Skin Cells

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Effect of an anthocyanidin-zeolite complex (A-Z) was investigated by real-time cell analysis in cultured human epidermoid carcinoma keratinocytes (A431) and human forehead fibroblasts (HFF). A mesoporous zeolite, a potential adsorbent applied in household products, was complexed with an anthocyanidin, extracted from blue flowers of Clitoria ternatea Linn. The A-Z was linearly correlated within a range of 0.05 0.3 mg/ml of the anthocyanidin, analyzed by HPLC, in accordance to Langmuir adsorption isotherm (r = 0.992, p > 0.05). In comparison to zeolite or anthocyanidin alone, A431 and HFF showed significantly cell survival with improved IC50 upon exposure to A-Z (p < 0.05). The adsorbed anthocyanidin onto the zeolite reduced the toxic potentials of each.

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July 2013

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[1] K. Kasuma, N. Noda and M. Suzuki: Phytochemistry Vol. 64 (2003), p.1133.

Google Scholar

[2] A.Castañeda-Ovando, M. de L. Pacheco-Hernández, M. E. Páez-Hernández, J. A. Rodríguez and C.A. Galán-Vidal: Food Chem. Vol.113 (2009), p.859.

DOI: 10.1016/j.foodchem.2008.09.001

Google Scholar

[3] P.K. Mukherjee, V. Kumar, N.S. Kumar and M. Heinrich: J. Ethnopharmacol. Vol.120 (2008), p.291.

Google Scholar

[4] I. Serraino, L. Dugo, P. Dugo, L. Mondello, E. Mazzon, G. Dugo, A.P. Caputi and S. Cuzzocrea: Life Sci. Vol. 73 (2003), p.1097.

DOI: 10.1016/s0024-3205(03)00356-4

Google Scholar

[5] N. Kamkaen and J.M. Wilkinson: Phytother. Res. Vol. 23 (2009), p.1624.

Google Scholar

[6] X. Zhao, C. Zhang, C. Guigas, Y. Ma, M. Corrales, B. Tauscher and X. Hu: Eur. Food Res. Technol. Vol.228 (2009), pp.759-765.

DOI: 10.1007/s00217-008-0987-7

Google Scholar

[7] A.H. Janssen, I. Schmidt, C.J.H. Jacobsen, A.J. Koster and K.P. de Jong: Micropor. Mesopor. Mat. Vol. 65 (2003), p.59.

Google Scholar

[8] H.S. Cho and R. Ryoo: Micropor. Mesopor. Mat. Vol. 151 (2012), p.107.

Google Scholar

[9] R. Ryoo, S.H. Joo and S. Jun: J. Phy. Chem. B. Vol. 103(37) (1999), p.7743.

Google Scholar

[10] D.C. Thom, J.E. Davies, J.P. Santerre and S. Friedman: Oral Surg. Oral Med. Pathol. Oral Radiol. Endod. Vol. 95(1) (2001), p.101.

Google Scholar

[11] Y. Abe, M. Ueshige, M. Takeuchi, M. Ishii and Y. Akagawa: Int. J. Prosthodont. Vol. 16(2) (2003), pp.141-144.

Google Scholar

[12] S. Srirak, S. Porasuphatana, T. Damrongrungruang and A. Priprem: Thai J. Toxicology Vol. 25(1) (2010), p.39.

Google Scholar

[13] J.H. Fentem and B.A. Botham: Altern. Lab. Anim. Vol. 30(Suppl 2) (2002), p.61.

Google Scholar

[14] M. Ponnec: Int. J. Cosmetic Sci. Vol. 14 (1992), p.245.

Google Scholar

[15] Xing, J.Z., Zhu, L., Gabos, S. and Xie, L: Toxicol. in Vitro. Vol. 20 (2006), p.995.

Google Scholar

[16] Urcan, E., Haertela, U., Stylloua, M., Hickel, R., Scherthanc, H. and Reichla, F.X. Dent. Mater. Vol. 26 (2009), p.51.

Google Scholar

[17] Y.A. Abassi, B.Xi, W. Zhang, P. Ye, S.L. Kirstein, M.R. Gaylord, S.C. Feinstein, X.Wang and X. Xu: Chem. Biol. Vol. 16(7) (2009), p.712.

Google Scholar