In this paper, the design and manufacture technology of three dimensional(3D) integrated braided composite tube with flange are researched, including: braiding technology of 3D braided preform of tube with flange, the determination of process parameters of resin transfer molding(RTM) for 3D braided composite tube with flange, and the design of mould for consolidation of composite tube with flange. The fiber volume fraction of this component is calculated. The quality of composite tube with flange is good analyzed by ultrasonic A-scan. The maximum compressive force borne by composite tube flange is 56.65 kN, which has met the need of usage of 38 kN. The research result will provide a good way for designing and manufacturing high performance 3D integrated braided composite components with irregular shape.