Thermodynamics of Calcium Phosphate Porous Scaffold on Beta Phase Tricalcium Phosphate Effects

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Sucrose evaporation technique was applied to prepare porous ceramic scaffolds with multiphasic calcium phosphates. Compositions with Ca/P molar ratios of 1.67 with MgO were synthesized and subjected to a thermal treatment of up to 1050 °C to 1400 °C. The results show that various adjustable biphasic and multiphasic calcium phosphates can be prepared through vaporized filler amounts and controlled sintering temperature. The size of the pores in the final fabricated scaffolds with an interconnected network of pores ranged from several micro- to hundred micrometers of open pores. The phase amount of hydroxyapatite (HA) in the sintering process declined with elevated sintering temperature. The permeability of three-dimensional scaffolds used for tissue engineering was significant because it controlled the rate of cell migration and the diffusion of nutrients and waste products in and out of the scaffold.

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August 2013

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© 2013 Trans Tech Publications Ltd. All Rights Reserved

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