Effects of Velvet Antler Polypeptide-Collagen/Chitosan Materials on Proliferation of Osteoblast

Wen He Zhu; Jun Jie Xu; Wei Zhang; Yan Li; Xiao Jing Lu; Shi Jie Lv

doi:10.4028/www.scientific.net/AMM.380-384.4295

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HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 380-384Effects of Velvet Antler...

Effects of Velvet Antler Polypeptide-Collagen/Chitosan Materials on Proliferation of Osteoblast

Abstract:

A highly osteogenic hybrid bioabsorbable scaffold was developed for bone reconstruction. Though the use of a bioabsorbable collagen and chitosan scaffold for loading velvet antler polypeptide to repair bone defect and drug treatment. Velvet antler polypeptide and collagen were extracted for developing the compounded material. The SEM results show that the collagen and chitosan scaffold maintain the natural three dimensional network structures. The cell proliferation experiment result show that the can promote the osteoblast proliferation for a long time . These results indicated that this compound scaffold can sustainable to release drug and is a good material in bone defect and drug treatment.

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Periodical:

Applied Mechanics and Materials (Volumes 380-384)

Pages:

4295-4298

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.380-384.4295

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Online since:

August 2013

Authors:

Wen He Zhu, Jun Jie Xu, Wei Zhang, Yan Li, Xiao Jing Lu, Shi Jie Lv

Keywords:

Biomaterial, Bone Defect, Collagen, Velvet Antler Polypeptide

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