Mechanical States of Repaired Full-Thickness Defects of Articular Cartilage by Tissue Engineering under Compression

Yan Bao; Hai Ying Liu; Qing Liu; Li Lan Gao; Chun Qiu Zhang

doi:10.4028/www.scientific.net/AMM.395-396.658

Paper Titles

A Comparative Study on Preparation of High Strength Gypsum by Flue Gas Desulfurization Gypsum and Natural Gypsum
p.641

Research Progress of the Properties and Application of Bamboo Charcoal
p.646

Study on Loading Rate-Dependent Property of Different Layers in Articular Cartilage Based on ABAQUS
p.650

The Micro-Mechanical Behavior of Articular Cartilage under Continuous Sliding Load
p.654

Mechanical States of Repaired Full-Thickness Defects of Articular Cartilage by Tissue Engineering under Compression
p.658

The Impacts of Heat Treatment on the Material Structure and Properties of Mg-4.0Zn-1.0Ca-0.6Zr Bio-Medical Materials
p.662

Application of Melt Extrusion Process for an In Situ Polymers Blend of Cellulose with Polyethylene Glycol in the Presence of Ionic Liquid
p.667

Response Surface Optimization of Microwave-Assisted Extraction Conditions of Anthocyanins from Black Soybean Hull
p.672

Impact of DOM in Reclaimed Water on Nitrogen/Phosphate Adsorption in Sediments
p.678

HomeApplied Mechanics and MaterialsApplied Mechanics and Materials Vols. 395-396Mechanical States of Repaired Full-Thickness...

Mechanical States of Repaired Full-Thickness Defects of Articular Cartilage by Tissue Engineering under Compression

Abstract:

It is difficult to repair the damage cartilage by itself when cartilage is injured. Cartilage tissue engineering is an ideal treatment method to repair cartilage defects, but at present, the repair has some uncertain effects which is caused by the mechanical states of the repaired region. Under the compression, mechanical behaviors of the repaired full-thickness defect were analyzed by means of the digital correlation technology. Experiments show that in the direction of vertical cartilage surface, the maximum compressive strain of artificial cartilage is 1.7 times higher than the normal host cartilage at 5.1% compression, and it is 1.4 times higher than the normal host cartilage at 25.6% compression. In parallel to the cartilage surface direction, the interface appears compressive strain and the host cartilage near the interface presents a smaller tensile strain. In the aspect of shear strain, direction of shear strain at the junction changes to the opposite direction with the compressive increase.

You might also be interested in these eBooks

View Preview

Info:

Periodical:

Applied Mechanics and Materials (Volumes 395-396)

Pages:

658-661

DOI:

https://doi.org/10.4028/www.scientific.net/AMM.395-396.658

Citation:

Cite this paper

Online since:

September 2013

Authors:

Yan Bao, Hai Ying Liu, Qing Liu, Li Lan Gao, Chun Qiu Zhang

Keywords:

Articular Cartilage Defect, Compression Load, Digital Image Correlation (DIC), Mechanical States, Tissue Engineering

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

Citation:

References

[1] Dai, K.R., 2009. The mechanical biological studies of the bone and joint. J. Biomedical engineering. 24, 1.

Google Scholar

[2] Ahmed, T.A., Hincke, M.T., 2010. Strategies for articular cartilage lesion repair and functional restoration. Tissue Eng Part B Rev. 16, 305-29.

DOI: 10.1089/ten.teb.2009.0590

Google Scholar

[3] Zhang, S.Q., Zhang, C.Q., Gao, L.L., Sun, M.Q., Li, J., Liu, H.Y., 2011. Mechancal state research of tissue engineering repairing defect articular cartilage.J. Chinese tissue engineering and clinical recovery. 15, 3629-3632.

Google Scholar