Ni base alloy composite coating containing spheroidal ceramic grains can be fabricated by a vacuum fusion sintering method. Composite coating was mainly composed of Ni base alloy and spheroidal ceramic grains with random orientation. The three-phase model is used to determine the thermal expansion coefficient of the composite coating. First, Eshebly-Mori-Tanaka method was used to determine thermal disturbance strain in two-phase cell aroused thermal inconsistency. Then, average thermal strain in the two-phase cell aroused by thermal inconsistency is gained by the means of volume equilibration. The two-phase cell is transverse isotropy and has two independent thermal expansion coefficients. Finely, based on mean strain of Ni base alloy ceramic composite coating containing spheroidal ceramic grains, the effective thermal expansion coefficient of the composite coating is obtained by considering random orientation of two-phase cells. Ni base alloy composite coating containing spheroidal ceramic grains is isotropy and has one independent thermal expansion coefficient.