In this work the static and dynamic properties of vanadium alloy V-5Cr-5Ti over a wide range of temperature from 20 to 1000 degree at strain rates ranged from 10-4/s~103/s were studied experimentally under uniaxial quasi-static tension with MTS universal testing machine, uniaxial dynamic compression and tension with split Hopkinson bar system with temperature control. The stress-strain curves of V-5Cr-5Ti at various temperatures and various strain rates were obtained. Experimental data show that V-5Cr-5Ti behaves strain-rate sensitive and temperature dependent, for instance the material parameters yield stress, tensile strength and failure strain. And fracture mode of the material is also dependent on strain-rate and temperature. Based on experimental data the temperature-rate-dependent constitutive relations were established in the form of Johnson-Cook and Cowper-Symonds models which are widely used in numerical simulation of dynamic processes of structures under impact loading. The material microstructures and failure modes were analyzed using optical microscope, TEM etc, and results shows that the yield stress and strength are increased with strain rate. The brittle-ductile transition strain-rate is from 101/s to102/s.